Avicel® RC - 581 consisting of microcrystalline cellulose, is produced using direct compression, dry granulation, and wet granulation technologies. It serves various functions in pharmaceuticals and nutraceuticals, acting as a compression aid, filler, and immediate release agent.

Chemical Name: Cellulose, Microcrystalline, Cellulose, carboxymethyl ether, sodium salt

CAS Number: 9004-34-6

Labeling Claims: APE-free, Aflatoxin-free, Allergen-free, Aluminum-free, Amine-free, Antibiotics-free, BSE-free, Bisphenol A-free, Caffeine Free, Colorants-free, Dioxin-free, Dye Free, Endocrine Disruptor-free, Ethylene Oxide-free, GMO-free, Generally Recognized As Safe (GRAS), Glycerin-free, Halal, Hormones-free, Irradiation-free, Kosher, Latex-free, Mercury-Free, Monosodium Glutamate (MSG)-free, Natural Latex Rubber-Free, Nitrosamines-free, Non-GMO, Not Listed In California Proposition 65, PAH-free, PFAS-Free, PFOS-free, PHO (Partially Hydrogenated Oil)-Free, PVC-free, Palm Oil-free, Paraben-free, Perfluorooctanoic Acid-free, Pesticide-free, Phthalates-free, Plasticizer-free, Preservative-free, Solvent-free, Sugar-free, TSE-free, Tributyl Tin Compounds-Free, Triphenyl Tin Compounds-Free, Vegan, Vegetarian, Zinc-free

Certifications & Compliance: British Pharmacopeia (BP), Doping-Free, EU Cosmetic Regulation 1223/2009 Compliant, EXCiPACT, European Pharmacopeia (Ph. Eur.), European Regulation 396/2005/EC, FDA Compliant, FDA Food Safety Modernization Act (FSMA), FSSC 22000, Generally Recognized As Safe (GRAS), Halal, Hazard Analysis Critical Control Point (HACCP), ICH Q3C, IFRA Compliant, ISO 22000, ISO 9001, Japan Pharmacopeia (JP), Kosher, National Formulary (NF), Regulation (EU) No. 1272/2008, Regulation (EU) No. 231/2012, United States Pharmacopeia (USP), cGMP

Manufacturing Technology: Direct Compression, Dry Granulation, Wet Granulation

Synonyms: Crystalline cellulose, Micro Fibril Cellulose, Pyrocellulose

  • TypeDocument Name
View All Documents

Enhanced TDS

Identification & Functionality

Features & Benefits

Applications & Uses

Properties

Physical Form
Physico-Chemical Properties
ValueUnitsTest Method / Conditions
IdentificationPass--
Initial Viscosity (at 1.2% Dispersion)72 - 168cPs-
Moisture Content (Loss on Drying)max. 6%-
Assay for Carboxymethylcellulose Sodium8.3 - 13.8%-
Sieve Fraction (+60 mesh)max. 0.1% wt-
Sieve Fraction (+200 mesh)max. 35% wt-
pH6.0 - 8.0--
Residue on Ignitionmax. 5.0%-
Microbiological Values
ValueUnitsTest Method / Conditions
Aerobic Plate Countmax. 1,000cfu/g-
Yeast and Mold Countmax. 100cfu/g-
SalmonellaAbsent/10g-
E. coliAbsent/10g-
Staphylococcus aureusAbsent/10g-
Pseudomonas aeruginosaAbsent/10g-
Heavy Metals
ValueUnitsTest Method / Conditions
Heavy Metalsmax. 0.001%-
Note

*More restrictive than compendium

Nutritional Information

Typical Nutrient Information/100g

US EU/Australia/NZ
Total calories 33 cal 188 kcal
Calories from fat 0 cal 0 kcal
Total fat 0 g 0 g
Saturated fat 0 g 0 g
Cholesterol 0 mg 0 mg
Sodium 862 mg 862 mg
Salt 2 g 2 g
Total carbohydrate 94 g 0 g
Total dietary fiber 94 g 94 g
Insoluble fiber 86 g 86 g
Soluble fiber 8 g 8 g
Sugar 0 g 0 g
Protein 0 g 0 g
Vitamin A 0 g 0 g
Vitamin C 0 g 0 g
Vitamin D 0 g 0
Calcium 1 mg 1 mg
Iron 0.3 mg 0.3 mg
Ash 2 g 2 g
Magnesium 1 mg 1 mg
Potassium 0 mg 0 mg
Moisture 4 g 4 g

Regulatory & Compliance

Storage & Handling

Shelf Life
3 years
Storage Conditions

Unopened packages, stored under dry and cool conditions.