Avicel® RC - 581 consisting of microcrystalline cellulose, is produced using direct compression, dry granulation, and wet granulation technologies. It serves various functions in pharmaceuticals and nutraceuticals, acting as a compression aid, filler, and immediate release agent.

Chemical Name: Cellulose, Microcrystalline, Cellulose, carboxymethyl ether, sodium salt

CAS Number: 9004-34-6

Labeling Claims: APE-free, Allergen-free, Aluminum-free, Antibiotics-free, BSE-free, Bisphenol A-free, Caffeine Free, Colorants-free, Dioxin-free, Dye Free, Endocrine Disruptor-free, Ethylene Oxide-free, GMO-free, Generally Recognized As Safe (GRAS), Glycerin-free, Halal, Hormones-free, Kosher, Latex-free, Monosodium Glutamate (MSG)-free, Natural Latex Rubber-Free, Non-GMO, PAH-free, PFAS-Free, PFOS-free, PHO (Partially Hydrogenated Oil)-Free, PVC-free, Palm Oil-free, Paraben-free, Perfluorooctanoic Acid-free, Pesticide-free, Phthalates-free, Plasticizer-free, Preservative-free, Sugar-free, TSE-free, Tributyl Tin Compounds-Free, Triphenyl Tin Compounds-Free, Vegetarian

Certifications & Compliance: British Pharmacopeia (BP), Doping-Free, EU Cosmetic Regulation 1223/2009 Compliant, EXCiPACT, European Pharmacopeia (Ph. Eur.), European Regulation 396/2005/EC, FDA Compliant, FDA Food Safety Modernization Act (FSMA), Generally Recognized As Safe (GRAS), Halal, ICH Q3C, IFRA Compliant, Japan Pharmacopeia (JP), Kosher, National Formulary (NF), Regulation (EU) No. 1272/2008, Regulation (EU) No. 231/2012, United States Pharmacopeia (USP), cGMP

Manufacturing Technology: Direct Compression, Dry Granulation, Wet Granulation

Synonyms: Crystalline cellulose, Micro Fibril Cellulose, Pyrocellulose

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Enhanced TDS

Identification & Functionality

Features & Benefits

Applications & Uses

Properties

Physical Form
Physico-Chemical Properties
ValueUnitsTest Method / Conditions
IdentificationPass--
Initial Viscosity (at 1.2% Dispersion)72 - 168cPs-
Moisture Content (Loss on Drying)max. 6%-
Assay for Carboxymethylcellulose Sodium8.3 - 13.8%-
Sieve Fraction (+60 mesh)max. 0.1% wt-
Sieve Fraction (+200 mesh)max. 35% wt-
pH6.0 - 8.0--
Residue on Ignitionmax. 5.0%-
Microbiological Values
ValueUnitsTest Method / Conditions
Aerobic Plate Countmax. 1,000cfu/g-
Yeast and Mold Countmax. 100cfu/g-
SalmonellaAbsent/10g-
E. coliAbsent/10g-
Staphylococcus aureusAbsent/10g-
Pseudomonas aeruginosaAbsent/10g-
Heavy Metals
ValueUnitsTest Method / Conditions
Heavy Metalsmax. 0.001%-
Note

*More restrictive than compendium

Nutritional Information

Typical Nutrient Information/100g

US EU/Australia/NZ
Total calories 33 cal 188 kcal
Calories from fat 0 cal 0 kcal
Total fat 0 g 0 g
Saturated fat 0 g 0 g
Cholesterol 0 mg 0 mg
Sodium 862 mg 862 mg
Salt 2 g 2 g
Total carbohydrate 94 g 0 g
Total dietary fiber 94 g 94 g
Insoluble fiber 86 g 86 g
Soluble fiber 8 g 8 g
Sugar 0 g 0 g
Protein 0 g 0 g
Vitamin A 0 g 0 g
Vitamin C 0 g 0 g
Vitamin D 0 g 0
Calcium 1 mg 1 mg
Iron 0.3 mg 0.3 mg
Ash 2 g 2 g
Magnesium 1 mg 1 mg
Potassium 0 mg 0 mg
Moisture 4 g 4 g

Regulatory & Compliance

Storage & Handling

Shelf Life
3 years
Storage Conditions

Unopened packages, stored under dry and cool conditions.