METHOCEL™ E15 Premium LV HPMC

1 of 50 products in this brand
METHOCEL™ E15 Premium LV HPMC is a water-soluble product used in granulation and tablet coating manufacturing. It serves as a binder in ceramics and pharmaceuticals, functioning as a binder, immediate release agent, mucoadhesive, solubilizer, and sustained release agent.

INCI Name: Methylcellulose

Chemical Name: Hydroxypropyl Methylcellulose

CAS Number: 9004-65-3

Dosage Form: Suspension, Tablets

Ingredient Origin: Plant Origin

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Enhanced TDS

Identification & Functionality

Chemical Family
Cellulose & Cellulosics,
Cellulose Ethers
Chemical Name
Hydroxypropyl Methylcellulose
INCI Name
Methylcellulose
Ingredient Origin
Plant Origin
Cosmetic Ingredients Functions
Thickener
Pharma & Nutraceuticals Functions
Binder,
Controlled Release Agent,
Film Former,
Gelling Agent,
Immediate Release Agent,
Mucoadhesive,
Solubilizer,
Sustained Release Agent,
Viscosity Modifier
Plastics & Elastomers Functions
Binder,
Emulsifier,
Film Former,
Lubricant (Internal),
Plasticizer,
Rheology Modifier,
Surfactant
Technologies
Cosmetic Ingredients,
Pharmaceuticals & Nutraceuticals
Product Families
Pharmaceuticals & Nutraceuticals — Excipients
Binders & Disintegrants,
Emulsifiers & Stabilizers,
Formulation & Processing Aids,
Modified & Controlled Release,
Pharmaceutical Coatings,
Solvents & Solubilizers
Cosmetic Ingredients — Functionals
Rheology Modifiers

Features & Benefits

Food Ingredients Features
Cold Water Dispersible
Materials Features
Anti-settling Properties,
Good Gelling Behaviour,
Good Thickening Properties,
Good pH Stability,
Improved Adhesion,
Non-Ionic,
Water Soluble,
Wide pH Range

Applications & Uses

Markets
Healthcare & Pharma,
Personal Care
Applications
Personal Care — Beauty & Care
Oral Care
Healthcare & Pharma — Drug Delivery & Care Solutions
Oral
Segments
Dietary Supplement,
Pharmaceutical
Applications
Pharmaceutical — Immediate release
Dietary Supplement — Immediate release
Application Format
Rinse Off
Dosage Form
Suspension,
Tablets
Manufacturing Technology
Granulation,
Tablet Coating
Oral Care Applications
Mouthwash,
Toothpaste

Properties

Physical Form
Powder
Soluble In
Cold Water Soluble,
Organic Solvent Soluble,
Propylene Glycol Soluble,
Water Soluble
Physical Properties
ValueUnitsTest Method / Conditions
pH (at 2% solution)*5.0 - 8.0-USP/EP/JP/CHP
Microbiological Values
ValueUnitsTest Method / Conditions
E. coli*Absent/gCurrent USP Negative
Pseudomonas aeruginosa*Absent/1gCurrent USP Negative
Salmonella*Absent/10gCurrent USP Negative
Staphylococcus aureus*Absent/gCurrent USP Negative
Yeast and Mold Count*max. 100/gCurrent USP Total Count
Total Plate Count*max. 100/gCurrent USP Total Aerobic
Composition
ValueUnitsTest Method / Conditions
Hydroxypropoxyl Content*7.0 - 12.0%USP/EP/JP/CHP
Methoxyl Content*28.0 - 30.0%USP/EP/JP/CHP
Propylene Glycol*0.1%-
Dipropylene Glycol*0.1%-
Tripropylene Glycol*0.1%-
Dipropylene Glycol Monomethyl Ether*0.1%-
Tripropylene Glycol Monomethyl Ether*0.1%-
Specifications
ValueUnitsTest Method / Conditions
Opalescence*Pass-Current EP Opalescence
Color Evaluation*Pass-Current EP Solution Color
Identification*Pass--
Residual Solvent*Pass-Current USP/EP/JP
Sulfated Ash Content*max. 1.5%Current USP/EP/JP
Loss on Drying*max. 5.0%USP/EP/JP/CHP
Residue on Ignition*max. 1.5%USP/SP/CHP
Apparent Viscosity (at 20°C, 2% in water)*12.0 - 18.0mPa.sUSP/EP/JP/CHP
Apparent Viscosity (Target)*15mPa.s-
Heavy Metals
ValueUnitsTest Method / Conditions
Heavy Metals (as Lead)*max. 10mg/KgUSP/EP/JP/CHP
Note

*NF and Ph. Eur. ID tests; “A” and “B” on a quarterly basis. ID tests “C” (NF and Ph. Eur.) and “D” (Ph.Eur.) will be completed by exception only.

Regulatory & Compliance

Certifications & Compliance Search Terms
National Formulary (NF)
Chemical Inventories
AIIC (Australia),
CSCL (Japan),
DSL (Canada),
EINECS (EU),
ENCS (Japan),
ISHL (Japan),
KECI (Korea),
METI (Japan),
PICCS (Phillipines)
Quality Standards
EN ISO 9001:2015,
GMP,
ICH Q3D

Packaging & Availability

Packaging Type
Bags,
Boxes,
Drums,
Super Sacks