METHOCEL™ E6 Premium LV Capsule Grade HPMC

1 of 30 products in this brand
METHOCEL™ E6 Premium LV Capsule Grade HPMC is a versatile product with various applications and functions. Ideal for tablet coating, granulation, wet granulation, tablets, and capsules, it ensures controlled and immediate release. Free from sewage sludge, it serves as a thickener, solubilizer, viscosity modifier, binder, film former, gelling agent, and mucoadhesive, making it indispensable in pharmaceutical and nutraceutical formulations. Suitable for food containers and packaging, it boasts water solubility, ensuring quality performance in suspension formulations.

Chemical Name: Hydroxypropyl Methylcellulose

CAS Number: 9004-65-3

Dosage Form: Capsules, Suspension, Tablets

Labeling Claims: APE-free, Allergen-free, Aluminum-free, Antibiotics-free, Artificial Flavor-Free, Bactericide-free, Bisphenol A-free, CMR Substances-free, Caffeine Free, Colorants-free, Diethylene Glycol-free, Dioxin-free, Endocrine Disruptor-free, Ethylene Glycol-free, Fungicide-free, Gluten-free, Glycerin-free, Halal, Herbicide-free, Hormones-free, Hypoallergenic, Impurities-free, Low Aldehyde, Low Odor, Monosodium Glutamate (MSG)-free, NPE-free, Natural Latex Rubber-Free, Naturally Derived, No Artificial Sweeteners, PAH-free, PFAS-Free, PFOA-free, PFOS-free, PHO (Partially Hydrogenated Oil)-Free, PVC-free, Palm Oil-free, Paraben-free, Perfluorocarbon (PFC)-free, Pesticide-free, Phthalates-free, Plant-Based, Plasticizer-free, Potassium-free, Preservative-free, Quaternary Ammonium Salt-Free, Radioactive-free, Steroids Free, Sugar-free, Tributyltin (TBT) - Free, USP 232 Elemental Impurities Free, Vegan, Vegetarian, Zero Calorie

Certifications & Compliance: British Pharmacopeia (BP), CFDA Compliant (China), Directive 1333/2008/EC, Doping-Free, EC No.1907/2006, EXCiPACT, European Pharmacopeia (Ph. Eur.), European Regulation 396/2005/EC, FCC Compliant, FDA 21 CFR 172.874, FDA 21 CFR 182.1480, FDA Compliant, FDA Food Safety Modernization Act (FSMA), FFDCA, GMP, Generally Recognized As Safe (GRAS), Halal, ISO 14001, Japan Pharmacopeia (JP), National Formulary (NF), REACH Exempt (Europe), Regulation (EC) No. 1333/2008, Regulation (EU) No. 10/2011 (PIM), Regulation (EU) No. 2022/1396, Regulation (EU) No. 231/2012, United States Pharmacopeia (USP)

Manufacturing Technology: Granulation, Tablet Coating, Wet Granulation

Synonyms: Hydroxypropyl methyl cellulose ether, Methyl hydroxypropyl cellulose, Cellulose hydroxypropyl methyl ether, 2-Hydroxypropyl methyl cellulose, 2-Hydroxypropyl methyl cellulose ether, Hydroxypropyl methyl cellulose, HPMC, Hypermellose, Hypromellose

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Enhanced TDS

Identification & Functionality

Features & Benefits

Applications & Uses

Properties

Physical Form
Soluble In
Physical Properties
ValueUnitsTest Method / Conditions
OpalescencePass-Current EP Opalescence
Color EvaluationPass-Current EP Solution Color
Color (at 2% in Water)max. 42APHAPSM 100946
pH (at 2%)5.0 - 8.0-USP/EP/JP/CHP
Typical Properties
ValueUnitsTest Method / Conditions
Identification*Pass-USP/EP/JP/CHP
Residual Solvents*Pass-Current USP/EP/JP
Sulfated Ash Contentmax. 1.0%Current USP/EP/JP
Loss on Dryingmax. 3.0%USP/EP/JP/CHP
Residue on Ignitionmax. 1.0%USP/JP/CHP
Apparent Viscosity (at 20°C, 2% in Water)5.7 - 6.3mPa.sUSP/EP/JP/CHP
Microbiological Values
ValueUnitsTest Method / Conditions
E. coli*Absent/gCurrent USP/EP
Pseudomonas aeruginosa*Absent/gCurrent USP/EP
Salmonella*Absent/10gCurrent USP/EP
Staphylococcus aureus*Absent/gCurrent USP/EP
Yeast and Mold Count*max. 50/gCurrent USP/EP Total Count
Total Plate Count*max. 100/gCurrent USP/EP Total Aerobic
Composition
ValueUnitsTest Method / Conditions
Hydroxypropoxyl Content7.0 - 12.0%USP/EP/JP/CHP
Methoxyl Content28.0 - 30.0%USP/EP/JP/CHP
Total Chloride Contentmax. 0.28%Current JSFA
Propylene Chlorohydrins Contentmax. 0.1mg/kgPSM 102375
Heavy Metals
ValueUnitsTest Method / Conditions
Arsenic Content*max. 1.5mg/kgE464/Current CHP
Cadmium Content*max. 0.5mg/kgCurrent JECFA
Iron Contentmax. 100mg/kgPSM 101985
Lead Content*max. 10mg/kgUSP/EP/JP/CHP
Lead Content*max. 1mg/kgCurrent JECFA
Mercury Content*max. 0.1mg/kgCurrent JECFA
Note
  • All section names come under PHS.
  • The following specifications apply to sealed, unopened containers stored under the recommended conditions for the duration of the shelf life.
  • Loss on drying: This product meets the requirement of 3.0% max "as packaged" and will not exceed 5.0% during the stated life of the product.
  • Specification limits apply to the material as packaged in the original containers. They do not apply if the material has been repackaged, improperly stored, or if the package has been opened in an uncontrolled environment.
  • This product is certified to contain not more than 0.1% of each of the following components: Propylene glycol, Dipropylene glycol, Tripropylene glycol, Dipropylene glycol monomethyl ether and Tripropylene glycol monomethyl ether.
  • Audit Basis*

Regulatory & Compliance

Packaging & Availability