METHOCEL™ F4M Premium HPMC

1 of 50 products in this brand
METHOCEL™ F4M Premium HPMC is water-soluble and finds application in ceramics and pharmaceuticals. It acts as a binder, film former, gelling agent, mucoadhesive, solubilizer, suspension aid, thickener, and viscosity modifier. Produced through granulation, it serves various industrial and pharmaceutical functions.

INCI Name: Methylcellulose

Chemical Name: Hydroxypropyl Methylcellulose

CAS Number: 9004-65-3

Dosage Form: Tablets

Ingredient Origin: Plant Origin

Labeling Claims: Aluminum-free, Animal Products-free, Antibiotics-free, BSE-free, Bisphenol A-free, CMR Substances-free, Caffeine Free, Colorants-free, Dairy-free, Diethylene Glycol-free, Dioxin-free, Doping Substances-free, Endocrine Disruptor-free, Ethylene Glycol-free, Fragrance allergen-free, Hormones-free, Iodine-free, Irradiation-free, Kosher, Latex-free, Maleic Acid -Free, Monosodium Glutamate (MSG)-free, Non-GMO, PFAS-Free, PVC-free, Paraben-free, Pesticide-free, Phenylalanine-Free, Plasticizer-free, Potassium-free, Preservative-free, Quaternary Ammonium Salt-Free, Radionuclides Free, Residual Solvent -Free, Sewage Sludge Free, Steroids Free, TSE-free, Tributyltin (TBT) - Free

Synonyms: Hydroxypropyl methyl cellulose ether, Methyl hydroxypropyl cellulose, Cellulose hydroxypropyl methyl ether, 2-Hydroxypropyl methyl cellulose, 2-Hydroxypropyl methyl cellulose ether, Hydroxypropyl methyl cellulose, HPMC, Hypermellose, Hypromellose

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Enhanced TDS

Identification & Functionality

Chemical Family
Cellulose & Cellulosics,
Cellulose Ethers
Chemical Name
Hydroxypropyl Methylcellulose
INCI Name
Methylcellulose
Ingredient Origin
Plant Origin
Cosmetic Ingredients Functions
Thickener
Pharma & Nutraceuticals Functions
Binder,
Controlled Release Agent,
Film Former,
Gelling Agent,
Mucoadhesive,
Solubilizer,
Suspending Agent,
Thickener,
Viscosity Modifier
Technologies
Cosmetic Ingredients,
Pharmaceuticals & Nutraceuticals
Product Families
Pharmaceuticals & Nutraceuticals — Excipients
Binders & Disintegrants,
Emulsifiers & Stabilizers,
Formulation & Processing Aids,
Modified & Controlled Release,
Pharmaceutical Coatings,
Solvents & Solubilizers
Cosmetic Ingredients — Functionals
Rheology Modifiers

Features & Benefits

Labeling Claims
Aluminum-free,
Animal Products-free,
Antibiotics-free,
BSE-free,
Bisphenol A-free,
CMR Substances-free,
Caffeine Free,
Colorants-free,
Dairy-free,
Diethylene Glycol-free,
Dioxin-free,
Doping Substances-free,
Endocrine Disruptor-free,
Ethylene Glycol-free,
Fragrance allergen-free,
Hormones-free,
Iodine-free,
Irradiation-free,
Kosher,
Latex-free,
Maleic Acid -Free,
Monosodium Glutamate (MSG)-free,
Non-GMO,
PFAS-Free,
PVC-free,
Paraben-free,
Pesticide-free,
Phenylalanine-Free,
Plasticizer-free,
Potassium-free,
Preservative-free,
Quaternary Ammonium Salt-Free,
Radionuclides Free,
Residual Solvent -Free,
Sewage Sludge Free,
Steroids Free,
TSE-free,
Tributyltin (TBT) - Free

Applications & Uses

Markets
Healthcare & Pharma,
Personal Care
Applications
Personal Care — Beauty & Care
Oral Care
Healthcare & Pharma — Drug Delivery & Care Solutions
Oral
Healthcare & Pharma — Other Healthcare & Pharma Applications
Segments
Pharmaceutical
Applications
Pharmaceutical — Immediate release
Application Format
Rinse Off
Dosage Form
Tablets
Manufacturing Technology
Granulation,
Tablet Coating
Oral Care Applications
Mouthwash,
Toothpaste

Properties

Physical Form
Powder
Soluble In
Cold Water Soluble,
Water Soluble
Physical Properties
ValueUnitsTest Method / Conditions
OpalescencePass-Current EP
Color Evaluation (solution Color)Pass-Current EP
pH (at 2% solution)5.0 - 8.0-Current USP/EP/JP
Typical Properties
ValueUnitsTest Method / Conditions
Identification*Pass-Current USP/EP/JP
Residual Solvent*Pass-Current USP/EP/JP
Sulfated Ash Contentmax. 1.0%Current USP/EP/JP
Insoluble Matter (Water Insoluble Material)max. 0.03%PSM 101681
Moisture Content (Loss on Drying)max. 5.0%Current USP/EP/JP
Residue on Ignitionmax. 1.0%Current USP/EP/JP
Apparent Viscosity (at 20°C, 2% in water)2,663 - 4,970mPa.sCurrent USP/EP/JP
Insoluble Matter (Water Insoluble Material, Using graduated tubes)0.01mL-
Microbiological Values
ValueUnitsTest Method / Conditions
E. coli*Absent/gCurrent USP
Pseudomonas aeruginosaAbsent/1gCurrent USP
Salmonella*Absent/10gCurrent USP
Staphylococcus aureus*Absent/1gCurrent USP
Yeast and Mold Count (Total)*max. 100/gCurrent USP
Total Plate Count*max. 100/gCurrent USP
Composition
ValueUnitsTest Method / Conditions
Hydroxypropoxyl Content4.0 - 7.5%Current USP/EP/JP
Methoxyl Content27.0 - 30.0%Current USP/EP/JP
Heavy Metals
ValueUnitsTest Method / Conditions
Heavy Metals (as Lead)*max. 20mg/KgCurrent USP/EP/JP
Note
  • PHS - All section names come under PHS
  • *[AB]

Regulatory & Compliance

Certifications & Compliance
EXCiPACT,
European Pharmacopeia (Ph. Eur.),
FSSC 22000,
GMP,
ISO 14001,
ISO 9001,
Japan Pharmacopeia (JP),
National Formulary (NF),
Orthodox Union Kosher,
Regulation (EC) No. 1333/2008,
Regulation (EU) No. 67/548/EEC,
US DMF,
United States Pharmacopeia (USP)
Chemical Inventories
AICS (Australia),
AIIC (Australia),
CSCL (Japan),
DSL (Canada),
EINECS (EU),
ENCS (Japan),
IECSC (China),
ISHL (Japan),
KECI (Korea),
METI (Japan),
NDSL (Canada),
PICCS (Phillipines)
Quality Standards
EN ISO 9001:2015,
GMP,
ICH Q3D

Technical Details & Test Data

Nutritional Infromation
USA
Nutritional Information (per 100 g)
Carbohydrates (g) 0
Non-Digestible Carbohydrates (g) 93.5
Water (g) 5
Ash (g) (includes salt and iron) 1.5
Total Fat (g) 0
Saturated Fat (g) 0
Trans Fat (g) 0
Protein (g) 0

 

Additional Nutrient Information (per 100 g)
Calories (Energy) (kcal) 0
Cholesterol (mg) 0
Total Dietary Fiber (g) 0
Soluble Fiber (g) 93.5
Insoluble Fiber (g) 0
Sugars (g) 0
Added Sugars (g) 0
Sodium (mg) 390
Chloride (mg) 610
Potassium (mg) 0
Magnesium (mg) 0
Iron (mg) 15
Zinc (mg) 0
Total Vitamin A (IU) 0
Vitamin C (mg) 0
Thiamin (mg) 0
Riboflavin (mg) 0
Vitamin D (IU) 0
Niacin (mg) 0
Vitamin B6 (mg) 0
Calcium (mg) 0
Phosphorus (mg) 0

 

European Union
Nutritional Information (per 100 g)
Energy 748 kJ / 187 kcal
Fat 0 g
Of which saturates 0 g
Carbohydrates 0 g
Of which sugars 0 g
Fibre 93.5 g
Protein 0 g
Salt 1.5 g

 

Australia & New Zealand
Nutritional Information (per 100 g)
Energy (kJ) 748
Carbohydrates (g) 0
Dietary Fibre (g) 93.5
Water (g) 5
Ash (g) (includes salt and iron) 0.4
Total Fat (g) 0
Saturated Fat (g) 0
Trans Fat (g) 0
Protein (g) 0

Packaging & Availability

Packaging Type
Bags,
Boxes,
Drums,
Super Sacks