METHOCEL™ F50 Premium HPMC

1 of 30 products in this brand
METHOCEL™ F50 Premium HPMC a cellulose ether also known as hypromellose, serves various functions across capsule, suspension, tablet, granulation, and tablet coating applications. It acts as a binder, film former, gelling agent, mucoadhesive, solubilizer, thickener, and viscosity modifier. Notably, it is water-soluble, ensuring optimal formulation performance.

Chemical Name: Hydroxypropyl Methylcellulose

CAS Number: 9004-65-3

Dosage Form: Capsules, Suspension, Tablets

Labeling Claims: APE-free, Allergen-free, Aluminum-free, Antibiotics-free, BSE-free, Bisphenol Derivatives-free, CMR Substances-free, Caffeine Free, Dairy-free, Diethylene Glycol-free, Dioxane-free, Dye Free, Endocrine Disruptor-free, Ethylene Glycol-free, Fungicide-free, Gluten-free, Glycerin-free, Halal, Herbicide-free, Hormones-free, Iodide-free, Kosher, Latex-free, Low Odor, Monosodium Glutamate (MSG)-free, Natural Latex Rubber-Free, Non-GMO, PAH-free, PFAS-Free, PFOA-free, PFOS-free, PHO (Partially Hydrogenated Oil)-Free, PVC-free, Palm Oil-free, Paraben-free, Pareve, Persistent Organic Pollutants (POP)-free, Pesticide-free, Phthalates-free, Plasticizer-free, Potassium-free, Preservative-free, Quaternary Ammonium Salt-Free, Sugar-free, TSE-free, Tributyltin (TBT) - Free, Vegan, Vegetarian, Zero Calorie

Certifications & Compliance: Belgian Law And Codex Alimentarius Standards, British Pharmacopeia (BP), Chinese Pharmacopeia (ChP), EC No.1907/2006, EXCiPACT, European Pharmacopeia (Ph. Eur.), FDA 21 CFR 172.874, FDA 21 CFR 174.5, FDA 21 CFR 175.105, FDA 21 CFR 175.300, FDA 21 CFR 176.170, FDA 21 CFR 176.180, FDA Compliant, FDA Food Safety Modernization Act (FSMA), FSC Certified, GMP, Generally Recognized As Safe (GRAS), Halal, ICH Q3C, Indian Pharmacopeia, Japan Pharmacopeia (JP), Kosher, Nagoya Compliant, National Formulary (NF), REACH Exempt (Europe), Regulation (EU) No. 10/2011 (PIM), Swiss Ordinance (SR 817.023.21), United States Pharmacopeia (USP), Waste Electrical & Electronic Equipment Directive (WEEE), cGMP

Manufacturing Technology: Granulation, Tablet Coating

Synonyms: Hydroxypropyl methyl cellulose ether, Methyl hydroxypropyl cellulose, Cellulose hydroxypropyl methyl ether, 2-Hydroxypropyl methyl cellulose, 2-Hydroxypropyl methyl cellulose ether, Hydroxypropyl methyl cellulose, HPMC, Hypermellose, Hypromellose

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Enhanced TDS

Identification & Functionality

Features & Benefits

Applications & Uses

Properties

Physical Form
Soluble In
Physical Properties
ValueUnitsTest Method / Conditions
OpalescencePass-Current EP Opalescence
Color EvaluationPass-Current EP Solution Color
pH (at 2%)5.0 - 8.0-Current USP/EP/JP
Typical Properties
ValueUnitsTest Method / Conditions
Identification*Pass-Current USP/EP/JP
Residual Solvents*Pass-Current USP/EP/JP
Sulfated Ash Contentmax. 1.5%Current USP/EP/JP
Moisture Content (Loss on Drying)max. 5.0%Current USP/EP/JP
Residue on Ignitionmax. 1.5%Current USP/EP/JP
Microbiological Values
ValueUnitsTest Method / Conditions
E. coli*Absent/gCurrent USP
Pseudomonas aeruginosa*Absent/gCurrent USP
Salmonella*Absent/10gCurrent USP
Staphylococcus aureus*Absent/gCurrent USP
Yeast and Mold Count*max. 100/gCurrent USP Total Count
Total Plate Count*max. 100/gCurrent USP Total Aerobic
Composition
ValueUnitsTest Method / Conditions
Hydroxypropoxyl Content4.0 - 7.5%Current USP/EP/JP
Methoxyl Content27.0 - 30.0%Current USP/EP/JP
Heavy Metals
ValueUnitsTest Method / Conditions
Lead Content*max. 20mg/kg-
Note
  • All section names come under PHS.
  • The following specifications apply to sealed, unopened containers stored under the recommended conditions for the duration of the shelf life.
  • Specification limits apply to the material as packaged in the original containers. They do not apply if the material has been repackaged, improperly stored, or if the package has been opened in an uncontrolled environment.
  • This product is certified to contain not more than 0.1% of each of the following components: Propylene glycol, Dipropylene glycol, Tripropylene glycol, Dipropylene glycol monomethyl ether and Tripropylene glycol monomethyl ether.

Regulatory & Compliance