METHOCEL™ E5 Premium LV HPMC - Specialty

1 of 40 products in this brand
METHOCEL™ E5 Premium LV HPMC - Specialty is water-soluble and used in suspensions, granulation, and tablet coating. It functions as a binder, controlled release agent, film former, and gelling agent in pharmaceuticals and nutraceuticals, and as a binder in ceramics.

Functions: Anti-Settling Agent, Binder, Controlled Release Agent, Emulsifier, Film Former, Green Strength Enhancer, Lubricant (Internal), Plasticizer, Processing Aid, Rheology Modifier, Surfactant, Thickener

Chemical Name: Hydroxypropyl Methylcellulose

Chemical Family: Cellulose & Cellulosics, Cellulose Ethers

End Uses: Ceramics

Dosage Form: Tablets

Certifications & Compliance: British Pharmacopeia (BP), CFDA Compliant (China), Chinese Pharmacopeia (ChP), Directive 1333/2008/EC, Directive 2009/48/EC, Doping-Free, EU Packaging Directive (94/62/EC), EXCiPACT, European Pharmacopeia (Ph. Eur.), European Regulation 396/2005/EC, FCC Compliant, FDA 21 CFR 101.9, FDA 21 CFR 172.874, FDA 21 CFR 182.1480, FDA Compliant, FDA Food Safety Modernization Act (FSMA), FFDCA, FSSC 22000, GMP, Generally Recognized As Safe (GRAS), Halal, Hazard Analysis Critical Control Point (HACCP), ICH Q3C, IFANCA Halal, ISO 14001, ISO 9001, Indian Pharmacopeia, Japan Pharmacopeia (JP), National Formulary (NF), Organic Certified, Orthodox Union Kosher, Regulation (EC) No. 1333/2008, Regulation (EU) No. 10/2011 (PIM), Regulation (EU) No. 1169/2011, Regulation (EU) No. 1272/2008, Regulation (EU) No. 1829/2003, Regulation (EU) No. 1830/2003, Regulation (EU) No. 2022/1396, Regulation (EU) No. 231/2012, USDA Organic, United States Pharmacopeia (USP), cGMP

Features: Anti-settling Properties, Cold Water Dispersible, Good Gelling Behaviour, Good Thickening Properties, Good pH Stability, High Cohesion, Improved Adhesion, Improved Dispersion, Low Ash Content, Low Surface Tension, Non-Ionic, Non-Toxic, Thixotropic, Water Soluble, Wide pH Range

Technical Data SheetSafety Data Sheet
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Enhanced TDS

Identification & Functionality

Carrier
Methylene Chloride
Chemical Family
Cellulose & Cellulosics,
Cellulose Ethers
Chemical Name
Hydroxypropyl Methylcellulose
Ingredient Origin
Plant Origin
Industrial Additives Functions
Binder,
Processing Aid,
Thickener
Pharma & Nutraceuticals Functions
Controlled Release Agent
Plastics & Elastomers Functions
Anti-Settling Agent,
Binder,
Emulsifier,
Film Former,
Green Strength Enhancer,
Lubricant (Internal),
Plasticizer,
Rheology Modifier,
Surfactant
Technologies
Industrial Additives & Materials,
Pharmaceuticals & Nutraceuticals,
Plastics
Product Families
Pharmaceuticals & Nutraceuticals — Excipients
Modified & Controlled Release
Plastics — Polymer Additives
Rheology Modifiers
Industrial Additives & Materials — Processing Aids
Other Processing Additives

Features & Benefits

Labeling Claims
APE-free,
Aflatoxin-free,
Allergen-free,
Aluminum-free,
Animal Products-free,
Antibiotics-free,
BSE-free,
Bisphenol A-free,
Caffeine Free,
Colorants-free,
Dioxin-free,
Dye Free,
Endocrine Disruptor-free,
Glycerin-free,
Halal,
Hormones-free,
Hypoallergenic,
Irradiation-free,
Kosher,
Low Odor,
Monosodium Glutamate (MSG)-free,
Mycotoxins-free,
Natural Latex Rubber-Free,
Naturally Derived,
Nitrosamines-free,
Non-GMO,
Organic,
PAH-free,
PFAS-Free,
PFOS-free,
PHO (Partially Hydrogenated Oil)-Free,
PVC-free,
Palm Oil-free,
Paraben-free,
Pareve,
Perfluorooctanoic Acid-free,
Pesticide-free,
Phthalates-free,
Plant-Based,
Plasticizer-free,
Preservative-free,
Residual Solvent -Free,
Sewage Sludge Free,
Sugar-free,
TSE-free,
Tributyl Tin Compounds-Free,
Triphenyl Tin Compounds-Free,
VOC-free,
Vegan,
Vegetarian,
Zero Calorie
Food Ingredients Features
Cold Water Dispersible
Materials Features
Anti-settling Properties,
Good Gelling Behaviour,
Good Thickening Properties,
Good pH Stability,
High Cohesion,
Improved Adhesion,
Improved Dispersion,
Low Ash Content,
Low Surface Tension,
Non-Ionic,
Non-Toxic,
Thixotropic,
Water Soluble,
Wide pH Range

Applications & Uses

Markets
Building & Construction,
Healthcare & Pharma
Applications
Building & Construction — Building Materials
Other Building Materials
Healthcare & Pharma — Drug Delivery & Care Solutions
Oral
Segments
Industrial
Applications
Industrial — Agriculture
Industrial — Coatings and Inks
Dosage Form
Tablets
Manufacturing Technology
Tablet Coating
Industrial Additives End Use
Ceramics

Properties

Soluble In
Organic Solvent Soluble,
Propylene Glycol Soluble,
Water Soluble
Physical Properties
ValueUnitsTest Method / Conditions
pH (at 2% solution)*5.0 - 8.0-CE-8.7
Microbiological Values
ValueUnitsTest Method / Conditions
E. coli*Absent/gCE-92.1
Pseudomonas aeruginosa*Absent/1gCE-92.1
Salmonella*Absent/10gCE-92.1
Staphylococcus aureus*Absent/gCE-92.1
Yeast and Mold Count*max. 100/gCE-92.1
Total Plate Count*max. 100/gCE-92.1
Composition
ValueUnitsTest Method / Conditions
Hydroxypropoxyl Content*7.0 - 12.0%CE-91.25
Methanol Content (PPM, Residual Solvents)*28.0 - 30.0%CE-91.25
Sodium Chloride Content*max. 0.3%CE-15.2
Propylene Glycol*0.1%-
Dipropylene Glycol*0.1%-
Tripropylene Glycol*0.1%-
Dipropylene Glycol Monomethyl Ether*0.1%-
Specifications
ValueUnitsTest Method / Conditions
Opalescence*Pass-CE-91.4 According to EP
Color Evaluation*Pass-CE-91.4 According to EP
Transmittance*min. 79.0%CE-91.29
Identification*Pass-CE-91.5
Sulfated Ash Content (Residue on Ignition)*max. 1.5%CE-91.34
Moisture Content (Loss on Drying)*max. 5.0%CE-7.1
Apparent Viscosity*4.1 - 4.9mPa.sCE-91.9
Apparent Viscosity (Target)*4.5mPa.s-
Heavy Metals
ValueUnitsTest Method / Conditions
Heavy Metals (as Lead)*max. 20mg/KgCE-93.1
Screen Test
ValueUnitsTest Method / Conditions
Screen (< 63 micron, through 230 mesh)*min. 50%CE-91.30
Screen (< 149 micron, through 100 mesh)*min. 90%CE-91.30
Note

*NF and Ph. Eur. ID tests; “A” and “B” on a quarterly basis. ID tests “C” (NF and Ph. Eur.) and “D” (Ph.Eur.) will be completed by exception only.

Regulatory & Compliance

Certifications & Compliance
British Pharmacopeia (BP),
CFDA Compliant (China),
Chinese Pharmacopeia (ChP),
Directive 1333/2008/EC,
Directive 2009/48/EC,
Doping-Free,
EU Packaging Directive (94/62/EC),
EXCiPACT,
European Pharmacopeia (Ph. Eur.),
European Regulation 396/2005/EC,
FCC Compliant,
FDA 21 CFR 101.9,
FDA 21 CFR 172.874,
FDA 21 CFR 182.1480,
FDA Compliant,
FDA Food Safety Modernization Act (FSMA),
FFDCA,
FSSC 22000,
GMP,
Generally Recognized As Safe (GRAS),
Halal,
Hazard Analysis Critical Control Point (HACCP),
ICH Q3C,
IFANCA Halal,
ISO 14001,
ISO 9001,
Indian Pharmacopeia,
Japan Pharmacopeia (JP),
National Formulary (NF),
Organic Certified,
Orthodox Union Kosher,
Regulation (EC) No. 1333/2008,
Regulation (EU) No. 10/2011 (PIM),
Regulation (EU) No. 1169/2011,
Regulation (EU) No. 1272/2008,
Regulation (EU) No. 1829/2003,
Regulation (EU) No. 1830/2003,
Regulation (EU) No. 2022/1396,
Regulation (EU) No. 231/2012,
USDA Organic,
United States Pharmacopeia (USP),
cGMP

Packaging & Availability

Packaging Type
Bags,
Boxes,
Drums,
Super Sacks