METHOCEL™ VLV Premium HPMC

1 of 30 products in this brand
METHOCEL™ VLV Premium HPMC is a versatile industrial additive designed for various applications, including tablet coating, orally disintegrating films, capsules, suspensions, and granules. With high efficiency and water solubility, it offers excellent cohesion development, green strength, and water retention. It functions as a binder, emulsifier, lubricant, and surfactant make it indispensable across manufacturing processes. Additionally, it serves as a water retention agent, binder and resin, slip agent, coating system, mucoadhesive, film former, viscosity modifier, solubilizer, gelling agent, and immediate release agent. METHOCEL™ VLV Premium HPMC's improved pumpability and lubricating properties ensure easy handling, making it a go-to choice for industrial and pharmaceutical formulations.

Chemical Name: Hydroxypropyl Methylcellulose

CAS Number: 9004-65-3

Dosage Form: Capsules, Granules, Orally Disintegrating Films (ODFs), Suspension, Tablets

Labeling Claims: APE-free, Allergen-free, Aluminum-free, Antibiotics-free, Artificial Flavor-Free, Bactericide-free, Bisphenol A-free, CMR Substances-free, Caffeine Free, Colorants-free, Diethylene Glycol-free, Dioxin-free, Endocrine Disruptor-free, Ethylene Glycol-free, FSSC 22000, Fungicide-free, Gluten-free, Glycerin-free, Halal, Herbicide-free, Hormones-free, Impurities-free, Kosher, Low Aldehyde, Low Odor, Monosodium Glutamate (MSG)-free, NPE-free, Natural Latex Rubber-Free, Naturally Derived, No Artificial Sweeteners, Non-Toxic, Odor-free, PAH-free, PFAS-Free, PFOA-free, PFOS-free, PHO (Partially Hydrogenated Oil)-Free, PVC-free, Palm Oil-free, Paraben-free, Perfluorocarbon (PFC)-free, Persistent Organic Pollutants (POP)-free, Pesticide-free, Phthalates-free, Plant-Based, Plasticizer-free, Potassium-free, Preservative-free, Quaternary Ammonium Salt-Free, Radioactive-free, Residues-free, Solvent-free, Steroids Free, Sugar-free, Tributyltin (TBT) - Free, Vegan, Vegetarian, Zero Calorie

Certifications & Compliance: Belgian Law And Codex Alimentarius Standards, British Pharmacopeia (BP), CFDA Compliant (China), Chinese Pharmacopeia (ChP), Directive 1333/2008/EC, Directive 2011/62/EU, Directive 2012/19/EU, Directive 2023/915/EU, Doping-Free, EC No. 2023/2006, EC No.1907/2006, EFSA (European Food Safety Authority) Certified, EU Cosmetic Regulation 1223/2009 Compliant, EXCiPACT, European Parliament and Council Directive (E464), European Pharmacopeia (Ph. Eur.), European Regulation 396/2005/EC, FCC Compliant, FDA 21 CFR 172.874, FDA 21 CFR 174.5, FDA 21 CFR 175.105, FDA 21 CFR 175.300, FDA 21 CFR 176.170, FDA 21 CFR 176.180, FDA 21 CFR 182.1480, FDA Compliant, FDA Food Safety Modernization Act (FSMA), FFDCA, GMP, Generally Recognized As Safe (GRAS), Halal, ICH Q3C, Indian Pharmacopeia, JECFA (FAO/WHO), Japan Pharmacopeia (JP), Kosher, National Formulary (NF), REACH Exempt (Europe), Regulation (EC) No. 1333/2008, Regulation (EU) No. 10/2011 (PIM), Regulation (EU) No. 1169/2011, Regulation (EU) No. 1272/2008, Regulation (EU) No. 1935/2004, Regulation (EU) No. 231/2012, Regulations (EU) No. 1129/2011, SCF Listed, United States Pharmacopeia (USP), cGMP

Manufacturing Technology: Tablet Coating, Wet Granulation

Synonyms: Hydroxypropyl methyl cellulose ether, Methyl hydroxypropyl cellulose, Cellulose hydroxypropyl methyl ether, 2-Hydroxypropyl methyl cellulose, 2-Hydroxypropyl methyl cellulose ether, Hydroxypropyl methyl cellulose, HPMC, Hypermellose, Hypromellose

Technical Data SheetSafety Data SheetBrochure
  • TypeDocument Name
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Enhanced TDS

Identification & Functionality

Chemical Family
Cellulose Ethers
Chemical Name
Hydroxypropyl Methylcellulose
Pharma & Nutraceuticals Functions
Binder,
Coating System,
Film Former,
Gelling Agent,
Immediate Release Agent,
Mucoadhesive,
Solubilizer,
Thickener,
Viscosity Modifier
Technologies
Pharmaceuticals & Nutraceuticals
Product Families
Pharmaceuticals & Nutraceuticals — Excipients
Binders & Disintegrants,
Emulsifiers & Stabilizers,
Formulation & Processing Aids,
Modified & Controlled Release,
Other Excipients,
Pharmaceutical Coatings,
Solvents & Solubilizers

Features & Benefits

Labeling Claims
APE-free,
Allergen-free,
Aluminum-free,
Antibiotics-free,
Artificial Flavor-Free,
Bactericide-free,
Bisphenol A-free,
CMR Substances-free,
Caffeine Free,
Colorants-free,
Diethylene Glycol-free,
Dioxin-free,
Endocrine Disruptor-free,
Ethylene Glycol-free,
FSSC 22000,
Fungicide-free,
Gluten-free,
Glycerin-free,
Halal,
Herbicide-free,
Hormones-free,
Impurities-free,
Kosher,
Low Aldehyde,
Low Odor,
Monosodium Glutamate (MSG)-free,
NPE-free,
Natural Latex Rubber-Free,
Naturally Derived,
No Artificial Sweeteners,
Non-Toxic,
Odor-free,
PAH-free,
PFAS-Free,
PFOA-free,
PFOS-free,
PHO (Partially Hydrogenated Oil)-Free,
PVC-free,
Palm Oil-free,
Paraben-free,
Perfluorocarbon (PFC)-free,
Persistent Organic Pollutants (POP)-free,
Pesticide-free,
Phthalates-free,
Plant-Based,
Plasticizer-free,
Potassium-free,
Preservative-free,
Quaternary Ammonium Salt-Free,
Radioactive-free,
Residues-free,
Solvent-free,
Steroids Free,
Sugar-free,
Tributyltin (TBT) - Free,
Vegan,
Vegetarian,
Zero Calorie

Applications & Uses

Markets
Healthcare & Pharma
Applications
Healthcare & Pharma — Drug Delivery & Care Solutions
Oral
Healthcare & Pharma — Pharmaceutical Manufacturing
Excipients & Coatings
Segments
Dietary Supplement,
Pharmaceutical
Applications
Pharmaceutical — Immediate release
Dietary Supplement — Immediate release
Dosage Form
Capsules,
Granules,
Orally Disintegrating Films (ODFs),
Suspension,
Tablets
Manufacturing Technology
Tablet Coating,
Wet Granulation

Properties

Physical Form
Powder
Soluble In
Cold Water Soluble,
Water Soluble
Physical Properties
ValueUnitsTest Method / Conditions
OpalescencePass-CE-91.4 According To Ep
Color EvaluationPass-CE-91.4 According To Ep
Color (at 2% in water)max. 65APHACE-13.8
pH (at 2%)5.0 - 8.0-CE-8.7
Typical Properties
ValueUnitsTest Method / Conditions
Identification*Pass-CE-91.5
Sulphated Ash Content (Residue on Ignition)max. 1.5%CE-91.34
Moisture Content (Loss on Drying)max. 5.0%CE-7.1
Apparent Viscosity2.3 - 3.3mPa.sCE-91.9
Microbiological Values
ValueUnitsTest Method / Conditions
E. coli*Absent/gCE-92.1
Pseudomonas aeruginosa*Absent/gCE-92.1
Salmonella*Absent/10gCE-92.1
Staphlococcus aureus*Absent/gCE-92.1
Yeast and Mold Count*max. 100/gCE-92.1
Total Plate Count*max. 100/gCE-92.1
Composition
ValueUnitsTest Method / Conditions
Hydroxypropoxyl Content *4.0 - 7.5%CE-91.25
Methoxyl Content*27.0 - 30.0%CE-91.25
Methanol Content (Residual Solvents)*max. 3,000mg/kgPSM 101832 Class 2
Heavy Metals
ValueUnitsTest Method / Conditions
Arsenic Content*max. 1mg/kgCE-92.1
Cadmium Content*max. 1mg/kgCE-92.1
Heavy Metals (as Lead)*max. 20mg/kgCE-92.1
Mercury Content*max. 1mg/kgCE-92.1
Lead Content*max. 2mg/kgCE-92.1
Note
  • The following specifications apply to sealed, unopened containers stored under the recommended conditions for the duration of the shelf life.
  • All section names come under PHS
  • * Audit Basis[AB]

    • This product is certified to contain not more than 0.1% of each of the following components: Propylene glycol, Dipropylene glycol, Tripropylene glycol, Dipropylene glycol monomethyl ether and Tripropylene glycol monomethyl ether.

Regulatory & Compliance

Certifications & Compliance
Belgian Law And Codex Alimentarius Standards,
British Pharmacopeia (BP),
CFDA Compliant (China),
Chinese Pharmacopeia (ChP),
Directive 1333/2008/EC,
Directive 2011/62/EU,
Directive 2012/19/EU,
Directive 2023/915/EU,
Doping-Free,
EC No. 2023/2006,
EC No.1907/2006,
EFSA (European Food Safety Authority) Certified,
EU Cosmetic Regulation 1223/2009 Compliant,
EXCiPACT,
European Parliament and Council Directive (E464),
European Pharmacopeia (Ph. Eur.),
European Regulation 396/2005/EC,
FCC Compliant,
FDA 21 CFR 172.874,
FDA 21 CFR 174.5,
FDA 21 CFR 175.105,
FDA 21 CFR 175.300,
FDA 21 CFR 176.170,
FDA 21 CFR 176.180,
FDA 21 CFR 182.1480,
FDA Compliant,
FDA Food Safety Modernization Act (FSMA),
FFDCA,
GMP,
Generally Recognized As Safe (GRAS),
Halal,
ICH Q3C,
Indian Pharmacopeia,
JECFA (FAO/WHO),
Japan Pharmacopeia (JP),
Kosher,
National Formulary (NF),
REACH Exempt (Europe),
Regulation (EC) No. 1333/2008,
Regulation (EU) No. 10/2011 (PIM),
Regulation (EU) No. 1169/2011,
Regulation (EU) No. 1272/2008,
Regulation (EU) No. 1935/2004,
Regulation (EU) No. 231/2012,
Regulations (EU) No. 1129/2011,
SCF Listed,
United States Pharmacopeia (USP),
cGMP
Chemical Inventories
AICS (Australia),
DSL (Canada),
ENCS (Japan),
IECSC (China),
KECI (Korea),
NDSL (Canada),
PICCS (Phillipines)

Packaging & Availability

Packaging Type
Bags,
Boxes,
Drums,
Super Sacks