
- Chemical Name:Cellulose, Microcrystalline
- CAS Number:9004-34-6
- Dosage Form:Effervescent Tablets, Tablets, Capsules, Granules, Pellets, Orally Disintegrating Tablets (ODTs)
- Certifications & Compliance:National Formulary (NF)
- Manufacturing Technology:Dry Granulation, Wet Granulation, Direct Compression
Microcrystalline Cellulose is purified, partially depolymerized cellulose prepared by treating alpha cellulose obtained as a pulp from fibrous plant material with mineral acids. Several grades of Avicel® PH MCC are available varying in particle size distribution, density and moisture content.
Avicel® PH microcrystalline cellulose (MCC) is most often used as a compression Aid, filler, flow aid, and dry binder for tablets and capsules.
Avicel® PH-101 has a typical average particle size of 50 µm and moisture content between 3 and 5%. Avicel® PH-101 is primarily used for wet granulation, extrusion spherization and tablet compression. Avicel® PH MCC rapidly absorbs aqueous binder solution permitting faster addition of fluid as well as shorter wet massing time. At the same time, the water does not become bound water resulting in faster drying time and uniform granular properties.