Avicel® PH - 301

Microcrystalline Cellulose is purified, partially depolymerized cellulose prepared by treating alpha cellulose obtained as a pulp from fibrous plant material with mineral acids. Several grades of Avicel® PH MCC are available varying in particle size distribution, density and moisture content. Avicel® PH microcrystalline cellulose (MCC) is most often used as a filler, disintegrant, flow aid, and dry binder for tablets and capsules. Avicel® PH-301 has a typical average particle size of 50 µm with a high bulk density of approximately 0.4 g/cc, compared to 0.3 g/cc for most other Avicel® grades. Avicel® PH-301 is primarily used for high shear wet granulation and direct compression. The high bulk density provides increased flowability resulting in improved blending characteristics and tablet uniformity. The high density also helps improve consistency and throughput of the capsule filling process.