Effective as of May 1, 2025, we are pleased to announce that the IFF Pharma Solutions Division is now part of Roquette. Please read our press release for more information.
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IFF Pharma Solutions
Avicel® PH - 112
Functions:
Compression Aid, Filler, Binder, Immediate Release Agent
Manufacturing Technology:
Dry Granulation, Wet Granulation, Spheronization, Extrusion, Direct Compression
Dosage Form:
Tablets, Capsules, Granules, Pellets, Effervescent Tablets, Orally Disintegrating Tablets (ODTs)
Certifications & Compliance Search Terms:
National Formulary (NF)
Microcrystalline Cellulose is purified, partially depolymerized cellulose prepared by treating alpha cellulose obtained as a pulp from fibrous plant material with mineral acids. Several grades of Avicel® PH MCC are available varying in particle size distribution, density and moisture content. Avicel® PH microcrystalline cellulose (MCC) is most often used as a filler, disintegrant, flow aid, and dry binder for tablets and capsules. Avicel® PH-112 has a typical average particle size of 100 µm and lower moisture content of not more than 1.2%. Avicel® PH-112 is primarily used for direct compression, and dry granulation/roller compaction for moisture sensitive Active Ingredients (APIs). The particle size of Avicel® PH-112 provides good flow characteristics. When compressed, Avicel® PH MCC undergoes plastic deformation. The strength of MCC tablets results from hydrogen bonding between the plastically deformed, large surface area cellulose particles. MCC is recognized as the most compactable of any direct compression excipient.
IFF Pharma Solutions
Endurance® VE - 090
Functions:
Compression Aid, Filler, Binder
Manufacturing Technology:
Wet Granulation, Spheronization, Granulation, Extrusion, Direct Compression
Dosage Form:
Tablets, Capsules, Granules, Pellets, Orally Disintegrating Tablets (ODTs)
Certifications & Compliance Search Terms:
National Formulary (NF)
Microcrystalline Cellulose is purified, partially depolymerized cellulose prepared by treating alpha cellulose obtained as a pulp from fibrous plant material with mineral acids. Several grades of Avicel® PH MCC are available varying in particle size distribution, density and moisture content. Microcrystalline cellulose (MCC) is most often used as a filler, flow aid, and dry binder for tablets and capsules. Endurance® VE-090 has a typical average particle size of 100 µm. It is primarily used for direct compression, and dry granulation/roller compaction for dietary supplement applications. The particle size of Endurance® VE-090 provides good flow characteristics and compression profiles.
IFF Pharma Solutions
Ac-Di-Sol® SD - 711
Functions:
Disintegrant, Immediate Release Agent
Manufacturing Technology:
Direct Compression, Dry Granulation, Wet Granulation, Granulation, Extrusion
Dosage Form:
Effervescent Tablets, Tablets, Capsules, Granules, Orally Disintegrating Tablets (ODTs)
Certifications & Compliance Search Terms:
National Formulary (NF)
Ac-Di-Sol® Croscarmellose Sodium is an internally cross-linked sodium carboxymethylcellulose. It is the super disintegrant of choice for many immediate release formulations. Ac-Di-Sol® is an insoluble and hydrophilic polymer with excellent water uptake and rapid swelling properties; supporting faster disintegration and drug dissolution at lower use levels (2-3%). Ac-Di-Sol® can be used in all manufacturing processes, including higher shear wet granulation, fluid bed granulation, direct compression, and dry granulation. Besides its disintegrating properties, Ac-Di-Sol® Croscarmellose Sodium has good binding and compaction properties.
IFF Pharma Solutions
Endurance® VE - 050
Functions:
Compression Aid, Filler, Binder
Manufacturing Technology:
Wet Granulation, Spheronization, Extrusion, Direct Compression
Dosage Form:
Tablets, Capsules, Granules, Pellets, Orally Disintegrating Tablets (ODTs)
Certifications & Compliance Search Terms:
National Formulary (NF)
Microcrystalline Cellulose is purified, partially depolymerized cellulose prepared by treating alpha cellulose obtained as a pulp from fibrous plant material with mineral acids. Several grades of Avicel® PH MCC are available varying in particle size distribution, density and moisture content. Microcrystalline cellulose (MCC) is most often used as a filler, flow aid, binder, and compression aid for tablets and capsules. Endurance® VE-050 has a typical average particle size of 50 µm. It is primarily used for wet granulation, direct compression, and extrusion/spheronization for dietary supplement applications.
IFF Pharma Solutions
Ac-Di-Sol® SDW - 802
Functions:
Disintegrant, Immediate Release Agent
Manufacturing Technology:
Direct Compression, Dry Granulation, Wet Granulation, Granulation, Extrusion
Dosage Form:
Effervescent Tablets, Tablets, Capsules, Granules, Orally Disintegrating Tablets (ODTs)
Certifications & Compliance Search Terms:
National Formulary (NF)
Ac-Di-Sol® SDW - 802 is a versatile ingredient suitable for capsules, granules, and orally disintegrating tablets (ODTs). Employing wet granulation, it serves as a disintegrant and immediate release agent in pharmaceutical and nutraceutical formulations.
IFF Pharma Solutions
AFFINISOL™ HPMC HME 15LV
Functions:
Controlled Release Agent, Anti-Crystallizing Agent, Solubilizer, Immediate Release Agent
Manufacturing Technology:
Hot Melt Extrusion, Spray Drying, Extrusion
Dosage Form:
Other Dosage Forms
Certifications & Compliance Search Terms:
National Formulary (NF)
AFFINISOL™ HPMC HME 15LV is a versatile polymer used in hot melt extrusion and spray drying manufacturing technologies. It is soluble in both water and organic solvents, making it ideal for a variety of pharmaceutical formulations, enhancing solubility and stability.